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Giornale Italiano di Dermatologia e Venereologia 2018 June;153(3):429-31

DOI: 10.23736/S0392-0488.16.05129-4

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English

Linear ectopic sebaceous hyperplasia of the penis: the last memory of Tyson’s glands

Giovanni PAOLINO 1 , Luca M. MUSCARDIN 2, Chiara PANETTA 2, Michele DONATI 3, Pietro DONATI 2

1 Clinic of Dermatology, Sapienza University of Rome, Rome, Italy; 2 Laboratory of Dermatopathology, San Gallicano Institute, Rome, Italy; 3 Biomedical Campus, Department of Surgical Pathology, Rome, Italy


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Pathologists who find ectopic glands on the glans and/or on the prepuce, often describe them as Tyson’s glands. In this regard, the term Tyson’s glands can be replaced by two different descriptive expressions: papillomatosis corona penis and ectopic sebaceous glands. A 15-year-old Caucasian male patient presented to our Institute with multiple and asymptomatic circular skin colored-to-yellowish papules at the level of the foreskin, also affecting the shaft of the penis, where they assumed a linear feature. The histological examination revealed hyperplastic and dilated sebaceous glands, while in some areas these glands showed also a direct attachment with the epidermis. A lymphocytic infiltrate was also observed in one of the two specimens. A final diagnosis of linear ectopic sebaceous hyperplasia of the penis was made. According to the current report, the ectopic sebaceous hyperplasia of the penis can have a circular and a linear patter, as well as the presence and the absence of a lymphoid infiltrate. A correct clinical and pathological diagnosis are necessary to avoid unnecessary treatments and worries in the patients. In fact, not infrequently, this condition is confused with dermatological diseases as molluscum contagiosum, epithelioid granuloma, lymphangioma circumscriptum, multiple syringomas, lichen planus, and bowenoid papulosis.


KEY WORDS: Sebaceous gland hyperplasia - Penis - Granulation tissue - Papilloma

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