Home > Journals > Giornale Italiano di Dermatologia e Venereologia > Past Issues > Giornale Italiano di Dermatologia e Venereologia 2017 December;152(6) > Giornale Italiano di Dermatologia e Venereologia 2017 December;152(6):560-4

CURRENT ISSUE
 

ARTICLE TOOLS

Publication history
Reprints
Cite this article as

GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,311


eTOC

 

ORIGINAL ARTICLE  


Giornale Italiano di Dermatologia e Venereologia 2017 December;152(6):560-4

DOI: 10.23736/S0392-0488.17.05704-2

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

What’s new in the treatment of eczemas

Massimo GOLA 1 , Antonio CARPENTIERI 2, Francesco LOCONSOLE 2

1 Allergological and Occupational Dermatology, Azienda USL Toscana Centro, Florence, Italy; 2 Department of Dermatology, University of Bari, Bari, Italy


PDF  


BACKGROUND: We have conducted an open label, non-comparative study in order to assess the efficacy and tolerability of Dexyane Med in combination with corticosteroids in patients with chronic hand eczema (CHE) and contact eczema (CE) in a real-life setting.
METHODS: Twenty patients, 10 with CHE and 10 with CE, have been enrolled in the study. After the enrollment and the baseline evaluation, patients were treated with topical mometasone once daily and Dexyane Med once daily for one week, followed by Dexyane Med twice daily for three weeks. After the enrollment visit, patients were seen at the end of treatment, after four weeks. A telephone contact was foreseen at the second week. During the visits, mTLSS Score (CHE patients only), IGA Score and VAS for pruritus and pain were calculated. Patients’ satisfaction was recorded during the phone contact after two weeks of treatment and at the final visit. Tolerability was evaluated at the end of the study.
RESULTS: All patients experienced a remarkable improvement in mTLSS Score, IGA Score (from a mean of 2.8 to 0.5) and VAS (from 4.5 to 0.6 for pruritus and from 2.9 to 0.3 for pain). The treatment was well tolerated and all patients were satisfied or very satisfied either at the second week or at the end of the study.
CONCLUSIONS: Our study has shown that the treatment of chronic hand eczema and contact eczema with a medical device administered twice a day for three weeks, following a one week treatment in combination with a topical corticosteroid, is effective in decreasing the burden of symptoms and well tolerated. To confirm our data, further controlled trials are warranted in order to explore the efficacy and tolerability of Dexyane Med in different types of eczema.


KEY WORDS: Eczema - Dermatitis, contact - Therapy - Equipment and supplies

top of page

Publication History

Issue published online: October 18, 2017
Manuscript accepted: June 22, 2017
Manuscript received: May 31, 2017

Cite this article as

Gola M, Carpentieri A, Loconsole F. What’s new in the treatment of eczemas. G Ital Dermatol Venereol 2017;152:560-4. DOI: 10.23736/S0392-0488.17.05704-2

Corresponding author e-mail

massimo.gola@uslcentro.toscana.it