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Giornale Italiano di Dermatologia e Venereologia 2016 February;151(1):55-76

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Paraneoplastic skin disorders: a review

Denis MIYASHIRO, Jose A. SANCHES

Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil


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Paraneoplastic disorders are manifestations of internal malignancies without the direct action of the tumor. Its pathogenesis involves production of substances that interfere with cellular activity of distant tissues. Paraneoplasias may be the first sign of cancer, and clinicians should be familiarized with its manifestations in order to perform an early diagnosis of the underlying neoplasm. The aim of this review was to describe most common paraneoplastic skin diseases.

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