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Giornale Italiano di Dermatologia e Venereologia 2013 December;148(6):699-702

Copyright © 2014 EDIZIONI MINERVA MEDICA

language: English

Transient symptomatic zinc deficiency resembling acrodermatitis enteropathica in a breast-fed premature infant: case report and brief review of the literature

Zattra E., Belloni Fortina A.

Dermatology Unit, Department of Medicine University of Padua, Padua, Italy


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Transient symptomatic zinc deficiency is a rare disorder clinically indistinguishable from acrodermatitis enteropathica characterized by periorificial and acral dermatitis that usually occurs in exclusively breast-fed infant especially if preterm. We describe a three-month-old breast-fed preterm boy who developed the typical skin lesions. Maternal breast milk zinc was lower than the levels from other 2 mothers of infants at the same gestational age. The disease improved and serum zinc level became normal with oral supplementation of zinc. No recurrence of the dermatosis was observed when the treatment was stopped after weaning.

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