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Giornale Italiano di Dermatologia e Venereologia 2003 February;138(1):35-6

Copyright © 2003 EDIZIONI MINERVA MEDICA

language: English

Localized pemphigus vegetans

Rampini P. 1, Parodi A. 2, Rampini E. 1, Gambini C. 3, Rebora A. 2

1 Department of Dermatology, Istituto Scientifico G. Gaslini, Genoa, Italy 2 Di.S.E.M Section of Dermatology, University of Genoa, Genoa, Italy 3 Department of Pathology, Istituto Scientifico G. Gaslini, Genoa, Italy


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The case of a patient with a plaque on her left clavicular area developing in about 9 months is described. Direct immunofluorescence from a perilesional area showed intercellular deposits of IgG and C3 in the epidermis. Granular deposits of C3 in a linear distribution were also present at the dermo-epidermal junction. No circulating autoantibodies were detected in the serum. The lesion improved in 2 months without any specific treatment. The term localized pemphigus vegetans for this form is proposed.

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