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Giornale Italiano di Dermatologia e Venereologia 2000 October;135(5):621-3

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: Italian

“Gloves and socks” syndrome caused by parvovirus B19

Cecchi R., Bartoli L., Brunetti L., Pavesi M., Giomi A.

U.S.L. 3, U.O. Dermatologia Spedali Riuniti di Pistoia


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The “gloves and socks” syndrome is a recently described acute and febrile dermatosis, which is characterized by a papulopetechial rash on the extremities in a typical “gloves and socks” distribution. Although several viruses have been involved as etiological agents for this syndrome, parvovirus B19 is the most common. The case of a 30-year-old patient presenting a typical erythematous and edematous eruption with purpura, localized on the hands and feet, associated with malaise, fever and sore throat is reported. In addition, there was a petechial enanthema on the palate and aphthous ulcers. The dermatosis resolved spontaneously within two weeks. Serologic investigations and PCR findings showed a primary infection due to parvovirus B19 in our patient.

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