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Giornale Italiano di Dermatologia e Venereologia 2000 June;135(3):359-62

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: Italian

Primary cutaneous anaplastic large cell lymphoma

Betto P., Gennari E., Gioia F.

Azienda Ospedaliera di Vicenza Divisione di Dermatologia * Reparto di Geriatria


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Anaplastic large cell lymphoma (ALCL) is clinically and pathologically heterogeneous. ALCL can be subdivided into different groups according to histologic features, immunophenotype and clinical features. A case of cutaneous lymphoma developed in a woman who was born in 1900, is described without any evidence of dissemination of lymphoma cells in other organs. The clinical lesion arose as a small papula in the inside area of the left thigh. At the moment of observation it was an ulcerated plaque which had an oval shape with greish base and prominent edges, and a diameter of 10¥15 cm. The histopathological findings showed un ALCL type T. Immunohistochemical analysis revealed markers CD30 in the lymphoma cell population. The recognition of this type of tumour is important because of its relatively good prognosis. It may prevent patients from unnecessary aggressive treatment.

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