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Giornale Italiano di Dermatologia e Venereologia 2000 February;135(1):83-5

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: Italian

Vasculitis to rifamycin in woman with tissue expander. Case report

Betto P., Gennari E., Bonoldi E. *, Martini Z. **

Azienda Ospedaliera di Vicenza Divisione di Dermatologia * Servizio di Anatomia Patologica ** Reparto di Chirurgia Plastica


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A case is reported of a 62-year old woman who, as a consequence of a tissue expander application for a silicone breast implant, observed the appearance of an erythematous plaque with purpuric lesions after the first swellings with a physiologic solution plus rifamycin. In a few days, this plaque spread, involving a large zone of the thoracic surface. The expander remotion determined a gradual resolution of the dermatosis. A skin biopsy showed a clinical picture of leucocytoclastic vasculitis. The expander was perfectly entire, and the microbiological tests performed on its liquid didn’t revealed the growth of bacteria and fungi. Thus, the clinical picture was attributed to rifamycin, that passing through the expander, may be the cause of a third-type allergic reaction.

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