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Giornale Italiano di Dermatologia e Venereologia 1999 October;134(5):461-75

Copyright © 1999 EDIZIONI MINERVA MEDICA

language: Italian

Primary cutaneous B-cell lymphomas

Manente L. 1, Muscardin L. M. 2, Peris K. 3, Anemona L. 4, Chimenti S. 3

1 Azienda Ospedaliera «S. Filippo Neri» - Roma, Servizio di Anatomia Patologica; 2 Ospedale «S. Gallicano» - Roma, Laboratorio di Istopatologia Cutanea; 3 Università degli Studi - L’Aquila, Clinica Dermatologica; 4 Università degli Studi «Tor Vergata» - Roma, Istituto di Anatomia Patologica


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The possibility that some lymphomas arise primarily in the skin and tend to remain localized to it for a long time, without a systemic spread, is a relatively new acquisition. In the present study, a review is made of primary cutaneous B-cell lymphomas according to lymphoma’s classifications proposed in the last years. The clinicopathologic features that differentiate primary cutaneous B-cell lymphomas from primary nodal and secondary cutaneous B cell lymphomas are underlined. Moreover, the similarities between primary cutaneous, B-cell lymphomas and other extra-nodal B-cell lymphomas (MALT lymphomas) are emphasized, reporting their diagnostic parameters. Primary cutaneous marginal zone B-cell lymphoma, a newly described entity, is also discussed.

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