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Giornale Italiano di Dermatologia e Venereologia 1999 October;134(5):415-20

Copyright © 1999 EDIZIONI MINERVA MEDICA

language: Italian

Evaluation of urethral bacterial flora in asymptomatic drug addict subjects

Filotico R. 1, Grande D. 2, De Vito D. 2, Loconsole F. 1, Pasca A. 1, Vena G. 3, Angelini G. 1

1 Università degli Studi - Bari, Clinica Dermatologica II; 2 Università degli Studi - Bari, Istituto di Igiene II; 3 Università degli Studi - Bari, ASL BA/4, SERT


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Background. The elevated frequency with which the sexually transmitted diseases (STD) appear in the immune-depressed subjects have induced to assess the incidence of the presence of pathogenous agents in the urethral passage of asymtomatic drug addict individuals.
Methods. A comparative study has been made between the urethral bacterial flora of asymptomatic drug addict subjects, HIV+ and HIV–, and 27 healthy subjects (i.e. not drug addicts and not HIV+). To this purpose, 50 drug addicts in treatment with metadone, 21 HIV+ and 29 HIV–, have been monitored in the period September 1995 - September 1996. All of them have been treated via urethral tampon in order to find bacterial flora and mycoplasma. The result of this examination has shown that no urethral pathology was active. Moreover an accurate anamnesis has been performed in order of investigate the sexual behaviours of the examinated individuals.
Results. The evaluation of the anamnestic results has pointed out substantial differences in the sexual behaviour of subjects in the three groups. The microbiologic research had confirmed that the Ureaplasma urealyticum is a microrganism frequently found also in absence of clinical symptomatology, especially in immuno-depressed HIV+.
Conclusions. The study underlines the usefulness of laboratory investigations to identify asymptomatic subjects as reservoir of pathogeneous microrganisms.

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