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CASE REPORT   

Chirurgia 2022 June;35(3):181-5

DOI: 10.23736/S0394-9508.21.05302-X

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Acromegaly and bariatric surgery: are they a solution for comorbidities?

Júlia IAROSESKI 1 , João V. GROSSI 2, Lucas F. ROSSI 2

1 Faculty of Medical Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil; 2 Unit of Digestive and General Surgery, Divina Providência Hospital, Porto Alegre, Brazil



Acromegaly is a syndrome characterized by increased secretion of growing hormone (GH). This syndrome is in by general caused by a pituitary adenoma that can be approached transsphenoidal pituitary surgery. Even though acromegaly is a rare syndrome, its comorbidities are relevant considering the correlation with morbimortality related to cardiovascular, respiratory and metabolic disorders. Even with successful hormonal treatment by GH seric levels stabilization after pituitary surgery, controlling comorbidities such as systemic arterial hypertension (SAH), sleep apnea and dyslipidemia seem to be a challenge in acromegaly therapy. Acromegaly is very commonly related to morbid obesity, which is an independent factor for all the comorbidities mentioned and has its surgical treatment well established to control these disorders. The reported case shows a 46-year-old female patient with acromegaly that drastically improved life quality after Roux-en-Y gastric bypass (RYGB) surgical intervention by solving comorbidities that were not attenuated even after 22 years of transsphenoidal hypophysis surgery. After a 180-day follow-up the clinical outcome achieved significant attenuation of SAH, dyslipidemia, sleep apnea and articular chronic pain. This case suggests, within its limitations, RYGB as an alternative to patients with obesity and acromegaly after hormonal and endocrinological stabilization, mainly after pituitary surgery.


KEY WORDS: Acromegaly; Obesity; Gastric bypass; Comorbidity

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