ORIGINAL ARTICLE   

Chirurgia 2020 August;33(4):193-6

DOI: 10.23736/S0394-9508.19.05039-3

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

The effect of pulsatile blood flow during proximal graft in facilitation weaning from cardiopulmonary bypass pump in coronary artery bypass graft surgery

Seyed M. AMOUZEGARZAVAREH ¹, Marzieh LAK ² ✉

¹ Atrosclrose Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran; ² Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

BACKGROUND: Even short time pulsatile flow can decrease the need for inotrope support and facilitate weaning from cardiopulmonary bypass. Thus clinical study was designed to investigate the effect of pulsatile flow during proximal graft in order to reduce the need for inotrope support during weaning from cardiopulmonary bypass (CPB) pump in coronary artery bypass graft (CABG) surgery.
METHODS: In this randomized clinical trial study 74 patients who underwent CABG surgery were randomly divided into two groups of a) pulsatile flow and b) non-pulsatile flow. Continuous blood flow was transferred to pulsatile blood flow during proximal graft by using cardiac contraction.
RESULTS: Our results clearly showed that using pulsatile flow significantly reduces the need for inotrope support.
CONCLUSIONS: It is suggested that pulsatile flow be induced by use of cardiac contraction during proximal graft in CABG surgery in the same way as our method which is mentioned in the body of the paper.

KEY WORDS: Pulsatile flow; Cardiopulmonary bypass; Surgery