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Chirurgia 2018 October;31(5):191-207

DOI: 10.23736/S0394-9508.18.04766-6

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Can cerebral disease cause cognitive disorders? A review of the literature

Majid R. FARROKHI 1, 2 , Mehrnaz GHOLAMI 1

1 Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 2 Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran


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The aim of the current review is to evaluate whether cerebral disease can cause cognitive disorders. We used different key words and medical database sources (e.g., Google Scholar, ISI Proceedings, Medline, Scopus, Web of Science) to search the literature for pertinent articles and reviews on cerebral disease and cognitive disorders dated from 1985 to 2017. This study shows that cerebral diseases can cause cognitive disorders and each of the cerebral diseases can adversely affect the functions of brain. Because human brain is involved in cognitive functions and it is a center for human communication with the surrounding environment and by accepting the fact that these features of the brain essentially distinguish humans from other animals (organisms), the brain involvement in different diseases according to their pathology and anatomical location of the lesion can result in an impairment of human cognition and eventually in various cognitive disorders. Therefore, the early recognition of those diseases is necessary to treat such disorders.


KEY WORDS: Cognition disorders - Cognitive dysfunction - Cerebral amyloid angiopathy - Brain edema - Hypoxia, brain - Cerebral palsy

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