Home > Journals > Chirurgia > Past Issues > Chirurgia 2017 December;30(6) > Chirurgia 2017 December;30(6):206-9

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as

 

CASE REPORT   

Chirurgia 2017 December;30(6):206-9

DOI: 10.23736/S0394-9508.17.04643-5

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Primary central nervous system lymphoma presenting as giant scalp tumor: a case report with review of literature

Ali M. AL-MASHANI 1 , Neeraj SALHOTRA 1, Azmat ALI 1, Maimuna S. AL SAADI 2

1 Department of Neurosurgery, Khoula Hospital, Muscat, Oman; 2 Department of Histopathology, Khoula Hospital, Muscat, Oman


PDF


Asymptomatic primary central nervous system lymphoma in an immuno-competent young adult patient with minimal intracranial but massive extra-cranial growth is extremely rare. We report a 27-year-old, asymptomatic female patient with exclusive complaint of a gradually increasing right parietal swelling over the last 8 months. The swelling over scalp measured 15 X 10 cm and the exact diagnosis remained inconclusive by CT, MRI, fine needle aspiration cytology and CSF examination. Craniotomy was performed believing it to be a meningioma. Immuno histo-chemistry of the excised lesion demonstrated neoplastic cells that were positive for CD20, PAX5, CD10, BCL6, MUM1; but negative for TdT1, BCL2, EBV-LMP1. These features were consistent with diffuse large B-cell lymphoma, germinal centertype. Fifteen months after the surgery that was followed by six cycles of chemotherapy, the patient remains asymptomatic without any evidence of systemic dissemination of the lymphoma.


KEY WORDS: Central nervous system - Lymphoma - Lymphoma, B-cell - Drug therapy

top of page