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CHIRURGIA

A Journal on Surgery


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Chirurgia 2017 October;30(5):160-2

DOI: 10.23736/S0394-9508.17.04604-6

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Malignant phyllodes tumor of the breast with spinal metastasis: case report and review of literature

Joseph A. SALAMEH 1, Elias M. ELIAS 1, Charbel M. ELIAS, Mohammed Y. AL GARNAWEE 1, Mark N. JABBOUR 2, Ghassan S. SKAF 1

1 Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon; 2 Department of Pathology, American University of Beirut Medical Center, Beirut, Lebanon


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Malignant phyllodes tumor is a rare neoplasm, usually detected on routine breast exams. Metastasis is unusual for this type of tumor and it mainly spreads via hematogenous routes. We present the case of a 54-year-old woman with thoracic spine metastasis of phyllodes tumor with osteosarcomatous differentiation 4 months following surgical resection of left breast mass. Malignant phyllodes tumors with osteosarcomatous differentiation are highly aggressive in nature and are unusual constituents of all breast cancers. Spinal metastasis of such tumor is rare and has been reported only among few cases in the literature. Surgical decompression with or without radiation is the best modality of treatment to relieve pain, regain neurological functions and prevent disease progression.


KEY WORDS: Breast neoplasms - Phyllodes tumor - Neoplasm metastasis - Spinal cord neoplasms

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Publication History

Issue published online: August 28, 2017
Manuscript accepted: February 8, 2017
Manuscript received: March 14, 2016

Cite this article as

Salameh JA, Elias EM, Elias CM, Al Garnawee MY, Jabbour MN, Skaf GS. Malignant phyllodes tumor of the breast with spinal metastasis: case report and review of literature. Chirurgia 2017;30:160-2. DOI: 10.23736/S0394-9508.17.04604-6

Corresponding author e-mail

gskaf@aub.edu.lb