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A Journal on Surgery

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Chirurgia 2014 August;27(4):237-9


language: English

A metastatic jejunal tumor from a small cell carcinoma of the lung found in an intestinal perforation

Palladino E. 1, Poiron L. 2, Lechner C. 1, Maestraggi Q. 2, Berger P. 2, Diebold M. D. 3

1 Department of General and Digestive Surgery, Chalons en Champagne Hospital, Chalons en Champagne, France; 2 Intensive Care Unit, Chalons en Champagne Hospital, Chalons en Champagne, France; 3 Department of Pathology, Reims University Hospital, Reims, France


Gastrointestinal metastases from a small cell lung cancer (SCLC) is relatively rare. From 2% to 14% of small bowel metastases is reported in autopsies. Symptoms usually emerge following a serious complications such as perforation, obstruction and upper gastrointestinal bleeding. We report the case of an acute abdomen due to jejunal perforation of gastrointestinal metastases from SCLC. The patient was a 43-year-old woman diagnosed with a metastatic SCLC in May 2012. She was treated with a first line chemotherapy including cisplatin, pemetrexed and bevacizumab. Intestinal obstruction, perforation and active upper gastrointestinal bleeding may occur in the end-stage of metastatic SCLC. Urgent palliative surgery is required and resection of the small bowel is often necessary with high risk for the patient. The clinic symptoms of the intestinal metastases of SCLC are rare and typically occur in the final stages of disease with a very poor prognosis. Recently various reports have shown the utility of PET[10] for the diagnosis.

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