CASE REPORTS   

Chirurgia 2014 February;27(1):65-9

Copyright © 2014 EDIZIONI MINERVA MEDICA

language: English

Extranodal non-Hodgkin’s lymphoma emerging on the lingual gingiva after extracting a fibrous tumor of bone from the mid mandible: a case report

Mochizuki Y. ¹, Omura K. ¹, Sakamoto K. ², Nakajima Y. ¹, Tushima F. ¹, Takahara N. ¹

¹ Oral and Maxillofacial Surgery Department of Oral Restitution Division of Oral Health Sciences, Graduate School Tokyo Medical and Dental University, Tokyo, Japan; ² Molecular Pathology, Department of Oral Restitution Division of Oral Health Sciences, Graduate School Tokyo Medical and Dental University, Tokyo, Japan

We describe a rare case of lymphoma diagnosed as extranodal non-Hodgkin’s lymphoma (NHL) emerging on the lingual gingiva in the mid mandible. The diagnosis was made by opening the labial alveolar bone a few years after a fibrous tumor of bone was extirpated from the mid mandible. To the best of our knowledge, no similar cases have been reported. In general, it was difficult to confirm whether the NHL involving the mandible and that emerging on the lingual gingiva originated in the intramandibular bone or in the surrounding soft tissue, because of a lack of evidence. Our present case could not also be confirmed. However, CT at the first visit showed slight cortical bone destruction while MRI indicated an osteomyelitis appearance. In addition, anesthesia of the left lower lip and skin of the chin was observed. Thus, we retrospectively considered that NHL of our present case had emerged from the intramandibular bone or surrounding soft tissue at the time of extirpation of intrabony fibrous tissue. If other cases present with clinical and radiological findings similar to those of our case, it will be important to consider strict follow up, multiple biopsies, and molecular studies such as flow cytometry.