ORIGINAL ARTICLES   

Chirurgia 2010 October;23(5):161-4

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: English

Testosterone ointment before hypospadias repair: clinical and surgical outcomes

Zampieri N.

Department of Anesthetic and Surgical Sciences, Pediatric Surgical Unit, Policlinico G.B. Rossi, University of Verona, Verona, Italy Department of Pediatrics and Obstetrician, “Orlandi” General Hospital, Bussolengo, Verona, Italy Casa di Cura “San Francesco” Hospital, Verona, Italy

Aim. Hypospadias is one of the most common malformation in childhood. Testosterone (TT) ointment before surgery seems to be useful to enlarge penile size to facilitate urethroplasty. The aim of this study was to evaluate and to report the useful of TT treatment.
Methods. We retrospectively reviewed the medical charts of patients who underwent hypospadias repair between June 1999 and June 2009. Patients were divided into two groups: patients which received testosterone oinment before surgery and patients that underwent surgery without testosterone treatment. Inclusion criteria were created. We evaluated the complication rate between groups (cosmetic and functional aspects) and the secondary effect of treatment.
Results. During the study period 53 patients were considered for the study (20 patients received TT ointment). After surgery cosmetic and functional results between groups were similar without statistical differences; patients with testosterone treatment before surgery had a similar complication respect to the others. (p<0.05).
Conclusion. Testosterone treatment seems to be useful to enlarge the penile size to facilitate surgeon during urethroplasy; this treatment is not associated with surgical complications.