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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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The Journal of Cardiovascular Surgery 2018 Mar 19

DOI: 10.23736/S0021-9509.18.10489-7

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

What are the remaining limitations of TAVI?

Chiara DE BIASE 1, 2, Antonios MASTROKOSTOPOULOS 1, Raphael PHILIPPART 1, Laurent BONFILS 1, Pierre BERTHOUMIEU 1, Nicolas DUMONTEIL 1

1 Groupe Cardio-Vasculaire Interventionel (GCVI), Clinique Pasteur, Toulouse, France; 2 Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy


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Transcatheter aortic valve implantation (TAVI) is a recognized therapy for patients with symptomatic severe aortic stenosis (AS). TAVI is superior compared to medical therapy as for mortality in extreme-risk patients, is non-inferior or superior to surgery in high- risk patients and non-inferior to surgery in intermediate-risk patients. However, several limitations affect outcomes after TAVI. Adverse events related to this procedure, like vascular complications, need forpacemaker implantation, paravalvular regurgitation, can be factors limiting TAVI treatment in younger patients at lower risk, as well as uncertainties regarding valve durability. This review tries to figure out some of the main complications still unsolved after TAVI.


KEY WORDS: Heart Valve disease - TAVI - Aortic stenosis

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Publication History

Article first published online: March 19, 2018
Manuscript accepted: March 15, 2018
Manuscript received: March 9, 2018

Cite this article as

De Biase C, Mastrokostopoulos A, Philippart R, Bonfils L, Berthoumieu P, Dumonteil N. What are the remaining limitations of TAVI? J Cardiovasc Surg 2018 Mar 19. DOI: 10.23736/S0021-9509.18.10489-7

Corresponding author e-mail

ndumonteil@clinique-pasteur.com