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REVIEW  RECENT ADVANCES IN THE TREATMENT OF CAROTID ARTERY DISEASE 

The Journal of Cardiovascular Surgery 2019 June;60(3):325-31

DOI: 10.23736/S0021-9509.19.10910-X

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Clinical and surrogate endpoints in future studies on outcome of carotid revascularization

Ludovica ETTORRE 1, Luca GIOVANNACCI 1, Jos C. van den BERG 2, 3

1 Service of Vascular Surgery, Centro Vascolare Ticino, Ospedale Regionale di Lugano, sede Civico, Lugano, Switzerland; 2 Service of Interventional Radiology, Centro Vascolare Ticino, Ospedale Regionale di Lugano, sede Civico, Lugano, Switzerland; 3 Inselspital, Universitätsspital Bern Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie, Bern, Switzerland



This paper will provide a comparison of classical endpoints like stroke and mortality versus biochemical (non-STEMI) myocardial infarction and DW-MRI new brain lesions and will discuss the importance of cranial nerve lesion in CEA. An overview of possible endpoints of future randomized clinical trials will be given.


KEY WORDS: Cerebral revascularization; Carotid endarterectomy; Carotid arteries; Stents

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