REVIEW ARTICLES  VASCULAR SECTION 

The Journal of Cardiovascular Surgery 2002 June;43(3):349-57

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: English

Vascular restenosis. Basic science and clinical implications

Heckenkamp J., Gawenda M., Brunkwall J.

From the Department of Surgery Division of Vascular Surgery University of Cologne, Cologne, Germany

Car­di­o­vas­cular inter­ven­tions to cor­rect arte­rial occlu­sive dis­ease ­have excel­lent ­short-­term ­results, but ­long-­term ­patency is ­still seri­ously com­pro­mised by the devel­op­ment of resten­osis. ­This ­review ­will pro­vide a por­trait of the mech­a­nisms fol­lowing vas­cular ­injury, ­define the clin­ical ­scope of the ­problem and out­line devel­op­ments of dif­ferent ther­a­peu­tical strat­e­gies to pre­vent resten­osis.