ORIGINAL ARTICLES  VASCULAR PAPERS 

The Journal of Cardiovascular Surgery 2000 October;41(5):743-52

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: English

Radiofrequency induction heating for the treatment of aortic dissection in an animal model

Fujii H., Sawada S. *, Tanigawa N. *, Ito E. **, Imamura H.

From the Department of Thoracic and Cardiovascular Surgery and *Radiology Kansai Medical University 10-15 Fumizonocho, Moriguchi, Osaka 570-8507, Japan **Department of Pathology I, School of Medicine University of the Ryukyus, Nishihara, Nakagami, Japan

Background. In ­this ­study, radio­fre­quen­cy (RF) induc­tion heat­ing ther­a­py ­using a ­self-expand­ing Gianturco metal­lic ­stent (G-EMS) to ­treat ­acute aor­tic dis­sec­tion was eval­u­at­ed.
Methods. We eval­u­at­ed con­ver­gent RF induc­tion heat­ing of G-EMS in ­pigs. In ­group A (n=3), an aor­tic dis­sec­tion was creat­ed to deter­mine the nat­u­ral ­course of ­this ­lesion. In ­group B (n=4), 0.40 mm stain­less ­steel ­bare G-EMSs (2.5 cm, 10 ­bends) ­were ­placed in the aor­ta 5 to 7 ­days ­after dis­sec­tion, and RF induc­tion heat­ing was per­formed for 30 (n=2) or 45 (n=2) min­utes. In ­group C (n=6), G-EMSs ­with 0.10 mm fer­ro-­chrome ­wire mount­ed on alter­nat­ing ­stent ­legs ­were ­placed in the aor­ta 1 to 7 ­days ­after dis­sec­tion, and RF induc­tion heat­ing was per­formed for 10 min­utes.
Results. In ­group A, 2 ­pigs ­died ­from rup­ture of the ­false ­lumen. In ­group B, ­fusion of the dis­sec­tion ­flap was con­firmed his­to­log­i­cal­ly. However, all of the ­pigs ­died. In ­group C, all of the ­pigs tol­er­at­ed the pro­ce­dure, and ­fusion of the dis­sec­tion ­flap was con­firmed in all of the ­pigs.
Conclusions. This experi­men­tal ani­mal ­study sug­gest­ed ­that RF induc­tion heat­ing com­bined ­with G-EMS, if prop­er­ly ­applied, has a poten­tial to ­treat ­acute aor­tic dis­sec­tion.