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The Journal of Cardiovascular Surgery 1999 April;40(2):261-4

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: English

Primary antiphospholipid syndrome: a cause of catastrophic shunt thrombosis in the newborn

Deally C., Hancock B. J., Giddins N., Hawkins L., Odim J.

From the Children’s Heart Center Winnipeg, Manitoba, USA


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This is a ­unique ­report of ­systemic-to-pul­mo­nary ­artery ­shunt throm­boses sec­on­dary to pri­mary anti­phos­pho­lipid syn­drome and anti­thrombin III defi­ciency in a neo­nate ­with cya­notic con­gen­ital ­heart dis­ease. ­This ­infant ­with tri­cuspid ­atresia expe­ri­enced throm­boses of two mod­i­fied Bla­lock-­Taussig ­shunts en ­route to a bi-direc­tional ­cavo-pul­mo­nary ­shunt and poten­tial ­future ­Fontan oper­a­tion. ­Chronic war­farin anti­co­ag­u­la­tion has pre­vented addi­tional ­thrombo-­embolic ­events.

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