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The Journal of Cardiovascular Surgery 1998 December;39(6):803-5

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: English

Successful repair of cardio-Behçet’s disease with aortic and mitral regurgitation

Zaharia M., Sasaki Sh., Matsui Y., Shiiya N., Murashita T., Yasuda K.

From the Department of Cardiovascular Surgery Hokkaido University, Sapporo, Japan


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A ­case of ­Behçet’s dis­ease ­with car­diac involve­ment of ­aortic and ­mitral regur­gi­ta­tion is pre­sented. The ­patient under­went ­aortic and ­mitral ­valve replace­ment, ­along ­with pli­ca­tion of the ­ascending ­aorta. His­to­log­ical exam­ina­tion ­revealed ­chronic inflam­ma­tion ­with degen­er­a­tive ­changes, con­sis­tent ­with ­Behçet’s dis­ease. ­Anti-inflam­ma­tory ­therapy ­using pred­nis­o­lone was main­tained ­throughout the post­op­er­a­tive ­period. ­This is the ­first ­case of ­cardio-­Behçet’s dis­ease sur­gi­cally ­treated for ­both ­aortic and ­mitral ­valves ­with a suc­cessful ­long-­term sur­vival.

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