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Otorhinolaryngology 2021 Jul 06

DOI: 10.23736/S2724-6302.21.02341-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Combined therapeutic approach to disorders of balance in the elderly: a retrospective study

Davide A. GIULIANO

Service of Otorhinolaryngology, Giovanni Paolo Secondo Hospital, Ragusa, Italy


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BACKGROUND: The disorders of the balance in the elderly represent one of the most debated topics in the otoneurologic field with many clinical needs. In the present study we have evaluated the efficacy of combined therapy with vestibular rehabilitation and sulodexide, a glycosaminoglycan with antithrombotic and anti-inflammatory vascular properties, to improve the imbalance in elderly patients measured by stabilometric assessment performed by Tetra-ataxiometric device.
METHODS: A retrospective analysis was performed on 185 patients with age ≥ 65 years suffering from disorders of balance treated with sulodexide in association with vestibular rehabilitation for three months.
RESULTS: The Stability Index (ST) pass from 947.7 of the baseline to 331.0 at the end of treatment, with an improvement of around 65% (P<0.001). In particular 62.1% of patients had high responsiveness to treatment (ST normalization 50% higher than the baseline), 20.5% moderate responsiveness (ST normalization 50-30%) and 17.3% low responsiveness (ST normalization <30%). Dividing the patients observed in two groups, such as group A characterized by patients with a state of persistent dizziness (55%) and group B characterized by patients with chronic recurrent episodes of dizziness or objective vertigo (45%), the therapy showed best improvement in the group A (P<0.001)
CONCLUSIONS: The present study showed that the therapeutic approach consisting of vestibular rehabilitation associated with drug therapy with sulodexide could be useful in the treatment of balance disorders in the elderly. Further studies are needed to confirm these results.


KEY WORDS: Postural balance; Aged; Sulodexide; Vestibular diseases; Rehabilitation

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