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Otorinolaringologia 2004 December;54(4):203-6

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: Italian

The efficacy of hyaluronic acid foam in middle ear surgery in order to prevent secondary tympanosclerosis

Ferrara S., Sammartano D.

Clinica Otorinolaringoiatrica «R» Università degli Studi, Palermo


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Aim. The efficacy of hyaluronic acid foam in the prevention of middle ear adhesion and other structural abnormalities in guinea pigs undergoing experimental tympanoplasty or myringoplasty was investigated. The aim of the current study is to determine the efficacy of absorbable gelatin sponge of hyaluronic acid 0.2% as compared with absorbable gelatin sponge of physiologic solution in the prevention of adhesion and other associated structural abnormalities in the middle ears undergoing tympanoplasty or myringoplasty.
Methods. Results were compared to a group of 10 patients with absorbable gelatin sponge of hyaluronic acid 0.2% in the middle ear and a group of 10 patients with absorbable gelatin sponge of physiologic solution in the middle ear in tympanoplasty or myringoplasty.
Results. After 6 weeks residual sponges were removed. The study must show us the the prevention of adhesion and other associated structural abnormalities in the middle ears undergoing tympanoplasty or myringoplasty and the difference between 2 groups.
Conclusion. Results between 2 groups of patients were not statistically significant.

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