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Italian Journal of Dermatology and Venereology 2022 Jan 10

DOI: 10.23736/S2784-8671.21.07203-0


language: English

Early predictors of psoriatic arthritis: a delphi based consensus from Italian dermatology centers

Francesco MESSINA 1, Mario VALENTI 2, 3 , Piergiorgio MALAGOLI 4 , Annunziata DATTOLA 5, Paolo GISONDI 6, Martina BURLANDO 7, Paolo DAPAVO 8, Valentina DINI 9, Chiara FRANCHI 10, Francesco LOCONSOLE 11, Matteo MEGNA 12, Antonio COSTANZO 2, 3

1 Section of Dermatology and Venereology, Unit of Dermatology, Department of Medicine, University of Padua, Padua, Italy; 2 Dermatology, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy; 3 Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 4 IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; 5 Department of Dermatology, University of Rome Tor Vergata, Rome, Italy; 6 Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy; 7 Section of Dermatology, DISSAL, Ospedale-Policlinico San Martino, IRCCS, University of Genoa, Genova, Italy; 8 A.O.U. Città della Salute e della Scienza, PO Molinette, Turin, Italy; 9 U.O. Dermatologia, Università di Pisa, Pisa, Italy; 10 U.O. Dermatologia, IRCCS Galeazzi, Milan, Italy; 11 Department of Dermatology, University of Bari, Bari, Italy; 12 A.O.U. Federico II, Naples, Italy


BACKGROUND: Psoriatic arthritis (PsA) is an inflammatory condition which can affect up to 41% of psoriatic patients [1]. In 40-60% of patients, PsA can determine cartilage destruction and joint deformities, hereby heavily impacting physical function and quality of life, even increasing the risk of death compared to the general population[1]. PsA manifestations usually develop after psoriasis onset, therefore dermatologists play a crucial role in the detection of early signs of arthritis. In our study, we aimed to identify simply detectable clinical and ecographic signs of early PsA and to assess their reliability.
MATERIALS AND METHODS: We assessed the opinion of a group of expert dermatologists, who were asked to express their opinion on the level of association between the selected anamnestic, clinical or instrumental signs and the onset of psoriatic arthritis by giving a score to each item.
RESULTS: Psoriatic onycopathy, signs of dactylitis and ultrasonographic alterations of selected joints were, respectively, the dermatologic, rheumatologic and imaging signs which had the strongest significance in the opinion of the experts.
CONCLUSIONS: These signs should be carefully looked for during dermatological examinations in order to detect early PsA.

KEY WORDS: Psoriasis; Psoriatic arthritis; Ultrasonography

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