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Giornale Italiano di Dermatologia e Venereologia 2020 December;155(6):780-2

DOI: 10.23736/S0392-0488.16.05231-7

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English

Spastic quadriplegia following intradermal use of hydrogen peroxide in the tardive curettage procedure for the treatment of a giant congenital nevus

Andrea MOLINELLI 1, Emanuele COZZANI 2 , Martina BURLANDO 2, Pierluigi SANTI 3, Aurora PARODI 2, Francesco VENTURA 1

1 Department of Legal Medicine, IRCCS San Martino University Hospital, Genoa, Italy; 2 Department of Dermatology, Di.S.Sal., IRCCS San Martino University Hospital, Genoa, Italy; 3 Department of Plastic Surgery, IRCCS San Martino University Hospital, Genoa, Italy



The possible transformation of a giant congenital melanocytic nevi (GCMN) in malignant melanoma estimated from 0.05% to 40% depend on the size of the lesions. Many are the surgical procedures proposed, including: full or partial-thickness excisions, dermabrasion, curettage in the first weeks of life and laser treatment. The curettage technique has been proposed in the literature for the treatment of GCMN in the first few weeks of life and defined as a relatively atraumatic surgery procedure without general complications. The authors report the first case in the literature of embolization due to use of subcutaneous peroxide infiltration before a tardive curettage procedure in a newborn case of GCMN resulting in spastic quadriplegia with dystonic reaction. Consequently, a lawsuit, due to this medical malpractice, has been opened.


KEY WORDS: Quadriplegia; Curettage; Hydrogen peroxide

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