REVIEW  AUTOIMMUNE CUTANEOUS DISEASES AND PREGNANCY: MANAGEMENT AND TREATMENT 

Giornale Italiano di Dermatologia e Venereologia 2019 June;154(3):286-98

DOI: 10.23736/S0392-0488.18.06159-X

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Specific dermatoses of pregnancy other than pemphigoid gestationis

Roberto MAGLIE, Lavinia QUINTARELLI, Alice VERDELLI, Paolo FABBRI, Emiliano ANTIGA ✉, Marzia CAPRONI

Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy

Specific dermatoses of pregnancy are skin disorders that occur specifically during or immediately after pregnancy and cannot be found in non-pregnant patients. According to the current consensus, they include atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), pemphigoid gestationis (PG), and intrahepatic cholestasis of pregnancy (ICP). The diagnosis of specific dermatoses of pregnancy can be challenging due to their variation in clinical presentation; moreover, the tests currently available do not always provide the clue for the diagnosis. However, some distinctive features may be helpful to differentiate between such entities. Accordingly, the knowledge of specific dermatoses of pregnancy and of their management is critical, since their early recognition may allow to provide care for the mother and prevent potential increased fetal risk. In fact, while AEP and PEP do not affect maternal and fetal prognosis, PG and, mainly, ICP are associated to maternal complications as well as the risk of fetal loss. In this paper, the epidemiology, pathogenesis, clinical features as well as management of AEP and PEP are reviewed in detail, while PG is described in another article of this issue. Moreover, the main features of ICP, which cannot be considered a primarily skin disease but may be managed first by dermatologists, are reported.

KEY WORDS: Pemphigoid gestationis; Dermatoses, pruritic urticarial papules plaques of pregnancy; Dermatoses, intrahepatic cholestasis of pregnancy