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Giornale Italiano di Dermatologia e Venereologia 2019 February;154(1):42-9
DOI: 10.23736/S0392-0488.18.06113-8
Copyright © 2018 EDIZIONI MINERVA MEDICA
language: English
Pathogenesis and causations of systemic contact dermatitis
Chandler W. RUNDLE 1, Brian C. MACHLER 2, Sharon E. JACOB 3 ✉
1 School of Medicine, Loma Linda University, Loma Linda, CA, USA; 2 Department of Dermatology, NYU Ronald O. Perelman School of Medicine, New York, NY, USA; 3 Department of Dermatology, Loma Linda University, Loma Linda, CA, USA
Systemic contact dermatitis (SCD) describes a hypersensitivity reaction following systemic re-exposure of the inciting allergen in previously sensitized individuals. Plants, drugs, and metals are the most common causes of SCD. In individuals with obstinate dermatitis, it is imperative to deliver history-focused patch testing with subsequent avoidance and elimination of the compound.
KEY WORDS: Dermatitis, contact - Hypersensitivity - Etiology