REVIEWS  NEUROBIOLOGY OF THE SKIN 

Giornale Italiano di Dermatologia e Venereologia 2010 April;145(2):229-44

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Cutaneous manifestations of endocrine neoplasia

Lowenstein E. B. ¹, Lowenstein E. J. ² ✉

¹ Downstate Medical Center, State University of New York, New York, NY, USA; ² Brookdale Hospital University Medical Center, New York, NY, USA

Skin serves as a window to the wellbeing and disease in a person. The recognition of cutaneous markers of endocrine neoplasia can allow for the early diagnosis of tumors, for early treatment and ultimately prevention of morbidity and mortality secondary to malignancy. The following review outlines the various endocrine neoplasias which can present with cutaneous manifestations. The pathogenesis and general manifestations are reviewed as well as the cutaneous manifestations of the endocrine neoplasia. Diagnosis and management are discussed. A summary of the familial endocrine neoplastic syndromes, including the six Multiple Endocrine Neoplasia Syndromes are reviewed. A current understanding of this subject will allow for better diagnosis and recognition of endocrine tumors as they present with skin signs and symptoms.