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Giornale Italiano di Dermatologia e Venereologia 2006 June;141(3):243-56

Copyright © 2006 EDIZIONI MINERVA MEDICA

language: English

Advancing vaccination strategies for prevention and therapy of dermatological diseases

Walden P.

Department of Dermatology, Venerology and Allergy Clinical Research Group Tumor Immunology Charité – Universitätsmedizin Berlin Humboldt University, Berlin, Germany


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Vaccinology increasingly incorporates the rapidly accumulating new knowledge of the molecular and cellular pathology of diseases, and of the components and mechanisms of cellular and humoral immune responses. With the changes in paradigms, new vaccination strategies are developed and explored for infectious diseases, cancer, autoimmune disorders and allergies. While these strategies are still at early stages of development, vaccination is expected to become an important tool not only for prevention but also for treatment and management of diseases. Future vaccines are bound to be molecularly defined and accurately tailored to induce most effective immune responses. Diseases of the skin are, increasingly, targets for vaccine development. Moreover, because of its easy accessibility and its constitution as a major immune organ, future developments will aim for vaccine designs suitable for delivery via the skin.

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