ORIGINAL ARTICLES   

Giornale Italiano di Dermatologia e Venereologia 2001 October;136(5):339-43

Copyright © 2001 EDIZIONI MINERVA MEDICA

language: Italian

Inverted follicular keratosis. Failure of detection human papilloma virus

Betti R., Moneghini L., Tolomio E., Martino P., Varricchione E.

Università degli Studi - Milano Ospedale San Paolo, Milano Clinica Dermatologica IV * II Cattedra di Anatomia ed Istologia Patologica

Background. Inverted follicular keratosis (IFK) is a benign cutaneous neoplasia in which a possible viral origin has been suggested.
Methods. The presence of Human Papilloma Virus (HPV) have been searched by Immunocytochemical and Polymerase chain reaction techniques in a series of IFK.
Results. All the examined cases of IFK showed no evidence of HPV antigen.
Conclusions. According of this study IFK is not a HPV related lesion but an adnexal tumor without a casual relationship with infection.