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CASE REPORT   

Giornale Italiano di Dermatologia e Venereologia 1999 December;134(6):603-6

Copyright © 1999 EDIZIONI MINERVA MEDICA

language: Italian

Mycosis fungoides bullosa

De Simoni I. 1, Peris K. 1, Lunghi F. 2, Manente L. 3, Caracciolo E. 1, Chimenti S. 1

1 Università degli Studi - L’Aquila, Clinica Dermatologica; 2 Ospedale di Frosinone - Frosinone, Divisione di Dermatologia; 3 Ospedale S. Filippo Neri - Roma, Divisione di Anatomia Patologica


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An 80-year-old woman was examined for the presence of widespread, partially blistered, eroded lesions on the right lower extremity, which had developed since three months. In addition, infiltrated, erythematous-scaling plaques on the trunk and legs were present for 7 years and gradually increased in number and size. Routine laboratory examinations were within normal limits. Histological examination of a skin biopsy specimen from the bullous lesion showed a dense, band-like infiltrate located in the upper dermis, composed of small and medium-sized lymphocytes with cerebriform nuclei. In addition, Pautrier’s abscesses and a large intraepidermal bulla were present in the epidermis. Based on clinicopathologic findings the diagnosis of mycosis fungoides bullosa was made. According to the EORTC classification, bullous MF is considered an unusual but specific variant of MF showing clinical behavior similar to that of classical MF.

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