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The role of drug coating balloons for artery restenosis
Franco NESSI, Carlo SETACCI
Gianmarco de DONATO, Michelangelo FERRI, Andrea GAGGIANO, Francesco SETACCI
Paperback € 21,85
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DESCRIPTION
Despite technological developments in the percutaneous trasluminal angioplasty (PTA) of peripheral artery disease (PAD), restenosis remains one of the most important critical issue. The vascular injury determined by balloon-induced barotrauma has been proven to cause restenosis through four processes: 1) acute elastic recoil; 2) negative vascular remodeling; 3) thrombus formation; 4) inflammatory response leading to smooth muscle cells proliferation. Drug-eluting balloons (DEBs), also known as drug-coated balloons, represent the next step in the evolution of effective treatment strategies for atherosclerotic vascular disease. Stent technology, particularly the drug-eluting stents, solved much of the problems, and their use in coronary angioplasty has cemented over the years. However, development of late restenosis and neointimal hyperplasia coupled with the need for effective long-term antiplatelet therapy for preventing stent thrombosis meant that further evolution of technologies was needed to develop an effective therapy for extracardiac atherosclerotic vascular disease.
ABOUT THE AUTHORS
Franco NESSI. Vascular and Endovascular Surgery Unit, Mauriziano Umberto I Hospital, Turin, Italy
Carlo SETACCI. Vascular and Endovascular Surgery Unit, University of Siena, Italy
CHAPTER INDEX
Pathophysiology of arterial restenosis
C. Setacci, M. Tadiello, M. Tozzi, A. Tarallo, G. Palasciano, D. Benevento, G. de Donato, F. Setacci
Technologies of drug coated balloons
A. Gaggiano, S. Quaglino
History of conventional endovascular treatment of restenosis
M. Cariati, U. G. Rossi
Carotid restenosis
C. Setacci, M. Tadiello, M. Tozzi, A. Tarallo, G. Palasciano, D. Benevento, G. de Donato, F. Setacci
Drug coated balloon in coronary in-stent restenosis
D. Gerardi, G. Esposito, E. Stabile
Restenosis of upper-extremity arteries
F. Speziale, P. Sirignano, L. Capoccia, W. Mansour, S. Cuozzo
Restenosis of visceral arteries
F. Casali, M. Lenti
Restenosis of renal arteries
F. Casali, F. Verzini
Restenosis of femoro-popliteal arteries
M. Ferri, D. Psacharopulo
Restenosis of below the knee vessels
P. Veroux, A. Davì, G. Bernardini, M. Veroux, A. Giaquinta
Restenosis of vascular access
G. de Donato, E. Pasqui, G. Alba, G. Fino, C. Panzano, G. Mazzitelli, M. Giubbolini, D. Benevento, G. Palasciano, C. Setacci
