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Online ISSN 1827-1847
PERIPHERAL ARTERIAL DISEASES
Sixt S. 1, Zeller T. 2
1 Angiologikum, Center for Interventional Angiology, Medical Care Prof. Mathey/Prof. Schofer, Hamburg, Germany;
2 University Heart Center, Freiburg Bad Krozingen, Bad Krozingen, Germany
The safety and efficiency of directed atherectomy (DA) have consistently been demonstrated in multiple clinical trails. The mechanical excision of the intima, however, seems to induce a reasonable inflammatory response which limit the long term clinical benefit. To control this inflammatory process it has been proposed to apply antiproliferative drugs, via a paclitaxel coated balloon (DCB). The combination of DA and consecutively DCB has the potential to provide optimal vessel preparation and to improve drug uptake during balloon angioplasty.