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THE JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
Rivista di Medicina, Traumatologia e Psicologia dello Sport
Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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ORIGINAL ARTICLES EXERCISE PHYSIOLOGY AND BIOMECHANICS
The Journal of Sports Medicine and Physical Fitness 2016 March;56(3):241-8
The alpha-actinin-3 r577x polymorphism and physical performance in soccer players
Daniel B. COELHO 1, Eduardo PIMENTA 2, Izinara C. ROSSE 3, Christiano VENEROSO 3, Lenice K. BECKER 1, Maria R. CARVALHO 4, Guilherme PUSSIELDI 5, Emerson SILAMI-GARCIA 3 ✉
1 Desportive Center of Federal University of Ouro Preto, Ouro Preto, Brazil; 2 Sports Department School of Physical Education, Physiotherapy and Occupational Therapy, Federal University of Minas Gerais, Belo Horizonte, Brazil; 3 Department of General Biology, Laboratory of Human and Medical Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil; 4 Physical Education Department, Federal University of Maranhão, São Luis, MA, Brazil
BACKGROUND: The aim of this study was to investigate the association between ACTN3 genotype (RR, RX, and XX) and physical performance of 138 adult, professional, U-20 and U-17 years Brazilian first-division soccer players.
METHODS: The following three parameters were investigated: first, speed, using a 30-meter sprint test with speed measured at 10 meters, 20 meters, and 30 meters; second, muscular strength, using counter-movement-jump and squat jump tests; and third, aerobic endurance using the Yo-Yo endurance test. The athletes were ranked in ascending order according to their performance in each test. After which they were divided into quartiles and clustered according to genotype and allele frequency. The χ2 was used to compare the genotype frequencies (RR, RX and RR) and allele frequencies (R and X) within and between the different quartiles of performance rating.
RESULTS: No significant differences were observed in genotypic or allelic frequencies between different performance ratings. The ACTN3 genotype was not associated to any of the physical performance parameters.
CONCLUSIONS: Our study provides no ervidence for an assocviation between alpha-actinin-3 R577x genotypes and differences in physical performance in adult, professional, U-20 and U-17 years Brazilian first-division soccer players.