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THE JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
Rivista di Medicina, Traumatologia e Psicologia dello Sport
Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,111
ORIGINAL ARTICLES BODY COMPOSITION, NUTRITION AND SUPPLEMENTATION
The Journal of Sports Medicine and Physical Fitness 2012 April;52(2):170-4
Effect of methylsulfonylmethane supplementation on exercise – Induced muscle damage and total antioxidant capacity
Barmaki S. 1, Bohlooli S. 2, Khoshkhahesh F. 1, Nakhostin-Roohi B. 1 ✉
1 Islamic Azad University-Ardabil branch, Ardabil, Iran;
2 Ardabil University of Medical Science, Ardabil, Iran
AIM: The aim of this study was to evaluate effect of 10-day methylsulfonylmethane (MSM) supplementation on exercise-induced muscle damage.
METHODS: Eighteen healthy, non-smoking, active young men were recruited to participate in this study. Participants were randomized in a double-blind placebo-controlled fashion into two groups: MSM (M) (N.=9) and placebo (P) (N.=9). Subjects consumed daily either placebo (200 mL water) or MSM supplement (50 mg/kg MSM in 200 mL water) for 10 days. Afterward, participants ran 14 km. Blood samples were taken before supplementation, before exercise, immediately, 30 min, 2, 24 and 48 h after exercise.
RESULTS: CK and bilirubin significantly increased in P group 24 h after exercise compared to M group (P=0.041 and P=0.002, respectively). TAC increased immediately post, 30 min, 2 and 24 h after exercise just in M group (P<0.05). TAC showed significant increase in M group 2 and 24 h after exercise compared to P group (P=0.014 and P=0.033, respectively).
CONCLUSION: It seems that 10-day supplementation with MSM has allowed to decrease muscle damage via effect on antioxidant capacity.