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Rivista di Medicina, Traumatologia e Psicologia dello Sport

Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,111

Periodicità: Mensile

ISSN 0022-4707

Online ISSN 1827-1928


The Journal of Sports Medicine and Physical Fitness 2010 Marzo;50(1):93-8

(Biochemistry, Immunology, Kinanthropometry, Neurology, Neurophysiology, Ophtalmology, Pharmacology, Phlebology, etc.) 

 Original articles

Effect of different exercise intensities on oxidative stress markers and antioxidant response in trained cyclists

Muñoz D. 1, Olcina G. 1, Timón R. 1, Robles M. C. 1, Caballero M. J. 2, Maynar M. 1

1 Sports Sciences School, University of Extremadura, Spain;
2 Medicine School, University of Extremadura, Spain

Traditionally, physical activity has been associated with beneficial effects on the organism. However, exercise has been shown to increase the production of reactive oxygen species (ROS) to a point that can exceed antioxidant defences, causing oxidative stress. Characteristics of exercise such as the intensity or duration seem to be associated with oxidative damage. The aim of this study was to evaluate the effect of exercise of two different cycling intensities on oxidative stress and antioxidant response in trained males. Twenty male trained cyclists participated in this study. The maximal exercise test consisted of an incremental cycling test until voluntary exhaustion, and the submaximal test was a steady state at 75% V.O2max for 30 min on a cycloergometer. In maximal exercise test (16±4 min of cycling), the results showed an increase in malondialdehyde (MDA) from 40.6±2.0 to 45.4± 18.4 mM (p<0.05) in plasma and from 0.21±0.10 to 0.23±0.12 mmol/g Hb (P<0.05) in erythrocytes, also vitamin C increased in plasma from 3.80±1.60 to5.20±2.16 mg/mL (P<0.05) and it decreased from 130.5±34.7 to 83.4±30.0 mg/g hemoglobin (P<0.05) in erythrocytes, whereas there were no changes in vitamin E concentrations. In submaximal exercise, no significant differences were obtained in MDA, vitamin C or vitamin E. In conclusion, short time of high intensity cycling leads to oxidative stress increasing plasma and decreasing erythrocyte vitamin C levels.

lingua: Inglese


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