Ricerca avanzata

Home > Riviste > The Journal of Sports Medicine and Physical Fitness > Fascicoli precedenti > The Journal of Sports Medicine and Physical Fitness 1999 Dicembre;39(4) > The Journal of Sports Medicine and Physical Fitness 1999 Dicembre;39(4):275-81

FASCICOLI E ARTICOLI   I PIÙ LETTI   eTOC

ULTIMO FASCICOLOTHE JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS

Rivista di Medicina, Traumatologia e Psicologia dello Sport


Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,111

 

The Journal of Sports Medicine and Physical Fitness 1999 Dicembre;39(4):275-81

 ORIGINAL ARTICLES

Relationship ­between mod­er­ate inten­sity endu­rance train­ing vol­ume and nat­u­ral kill­er ­cell cyto­lyt­ic activ­ity

Lee E. G. 1, Fox M. E. 1, Meadows G. G. 2, Johnson E. C. 1, Blank S. E. 1

1 Department of Kinesiology and Leisure Studies, Washington State University, Pullman, WA, USA;
2 Department of Pharmaceutical Sciences, Washington State University, Pullman, WA, USA

Background. This ­study was ­designed to exam­ine the rela­tion­ship ­between endu­rance train­ing vol­ume and nat­u­ral kill­er ­cell (NK) cyto­lyt­ic activ­ity. We hypoth­e­sized ­that a ­dose depen­dent rela­tion­ship ­exists ­between ­forced tread­mill train­ing vol­ume and train­ing ­induced increas­es in NK ­cell cyto­lyt­ic activ­ity.
Methods. Experimental ­design: ­female, Swiss Webster ­mice ­were ­assigned to tread­mill con­trol (TC) or tread­mill ­trained ­groups (n=10 per ­group). Trained ­mice ran at 12 m per min. (8˚ ­grade) for: 15 (EX15), 30 (EX30), or 60 min­utes (EX60) per day, ­five ­days per ­week for 11 ­weeks. Splenic NK ­cell activ­ity was ­expressed as ­median lyt­ic ­unit (LU), ­median LU per asia­lo GM1 (AsGM1+) ­cell, and ­median LU per ­spleen.
Results. Median NK activ­ity was not sig­nif­i­cant­ly ­increased by train­ing vol­ume. A ­trend ­toward great­er ­median LU per AsGM1+ ­cell was ­observed in EX30 ­group ver­sus TC (p=0.1). Training vol­umes ­less ­than or great­er ­than ­this lev­el pro­duced small­er increas­es in NK cyto­lyt­ic activ­ity.
Conclusions. These ­data pro­vide pre­lim­i­nary evi­dence indi­cat­ing ­that train­ing ­induced increas­es in splen­ic NK ­cell cyto­lyt­ic activ­ity do not exhib­it a ­dose depen­dent rela­tion­ship ­with tread­mill train­ing vol­ume.

lingua: Inglese


FULL TEXT  ESTRATTI

inizio pagina