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Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,111
Online ISSN 1827-1928
Vasankari T., Kujala U., Sarna S., Ahotupa M.
MCA Research Laboratory and Paavo Nurmi Center, Department of Physiology, University of Turku, Turku;
Finnish Sports Institute, Vierumäki, Unit for Sports and Exercise Medicine, Institute of Biomedicine and Department of Public Health, University of Helsinki, Helsinki, Finland
Background. We studied the effects of supplementation of vitamin C and carbohydrate on acute exercise-induced lipid peroxidation.
Methods. Experimental design: two randomized controlled trials.
Participants: 17 endurance athletes. Interventions: in study I, nine athletes repeated twice a 10.5-km maximal run and ingested in a randomized single-blind order either 2.0 g vitamin C or placebo. In study II, eight athletes repeated twice a 27-km maximal run and ingested in randomly either 105 g carbohydrate or placebo. Venous blood samples were taken before the exercise, immediately after the exercise, and after a recovery period of 90 min (study I) or 120 min (study II). Measure: serum diene conjugation, lipid peroxidation.
Results. In study I, there was no difference in serum diene conjugation between the trials during exercise (pre- vs post-exercise). However, during the recovery period (post-exercise vs recovery sample) serum diene conjugation concentration decreased by 11% in the vitamin C trial but not in placebo (p=0.028). In study II, there was no difference between the carbohydrate and placebo trials.
Conclusions. Vitamin C and carbohydrate do not prevent exercise-induced increase in oxidative stress, but vitamin C, being a potent aqueous antioxidant, seems to decrease the levels of diene conjugation during recovery after exercise. The clinical significance of this phenomenon needs further evaluation.