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Panminerva Medica 2003 June;45(2):117-21

lingua: Inglese

Mechanisms of perinatal brain injury

Sabatino G. M. D., Domizio S., Cicioni P., Sabatino G.

Neonatal Intensive Care Unit University of Chieti, Chieti, Italy


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Perinatal ­brain ­injury is asso­ciated ­with path­o­log­ical con­di­tions ­caused by pathog­e­netic mech­a­nisms ­that ­remain ­unclear. Brain ­lesions can ­result not ­only ­from ­brain ­injury but may ­also orig­i­nate ­during ­fetal ­growth. Fetal enceph­a­lop­athy ­includes 4 ­groups of ­causes: ­maternal, ­fetal, pla­cental and ­idiopathic. Hypoxic-­ischemic ­lesions (per­i­ven­tric­ular leu­com­a­lacia and sub­cor­tical leu­com­a­lacia) and hem­or­rhage ­lesions (ger­minal hem­or­rhage) are dis­cussed.

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