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Panminerva Medica 2002 September;44(3):221-5

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

New antiepileptic drugs in childhood

Verrotti A., Trotta D., Morgese G., Chiarelli F.

Department of Paediatrics University of Chieti, Chieti, Italy *Department of Paediatrics University of Siena, Siena, Italy


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In ­recent ­years, ­many new anti­epi­leptic ­drugs ­have ­been avail­able for the treat­ment of epi­lepsy in pedi­atric age. In ­this ­review, we ­describe ­these new anti­epi­leptic ­drugs (vigab­a­trin, lamot­ri­gine, fel­ba­mate, gab­a­pentin, tia­ga­bine, topir­a­mate) ­which can be ­used ­together ­with “old” anti­epi­leptic ­drugs (e.g. phe­no­bar­bital, val­proate, etc.). We ­report ­their mech­a­nisms of ­action, effec­tive­ness, ­dosage and ­side ­effects; more­over, ­some prac­tical ­advice for ­their use in pedi­atric ­patients is ­given.

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