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Rivista di Medicina Interna
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,6
Panminerva Medica 2002 March;44(1):3-6
Scintigraphy with 99mTc-MIBI and echography in the study of primitive hyperparathyroidism
Falvo L., D’Andrea V., D’Ercole C., Grilli P., Catania A., Sorrenti S., Berni A., De Antoni E.
From the Division of General Surgery Department of Surgical Sciences University of Rome “La Sapienza”, Rome, Italy
Background. The authors analyse the value of the exames preoperative for the identification of the pathological parathyroid glands.
Methods. The authors examinated 58 patients affected by primitive hyerparathyroidism (HPTp) who had undergone surgical treatment for primary hyperparathyroidism at the Third Surgical Department of University “La Sapienza” of Rome, in 175 patients affected by primitive hyperparathyroidism observed between January 1970 and June 2000; all patients had undergone echotomography of the neck and 99mTc-MIBI scintigraphy in the diagnostic phase. The histological valuation confirmed the diagnosis by I.P.
Results. 99mTc-MIBI scintigraphy demonstrated the pathological glands in 56 cases (96.6%), the echography in 57 cases (98.2%). The comparison of the two exams demonstrated the pathological glands in 100% of the cases. In 45 cases the scintigraphy localized the side (77.6%), and the echography in 41 cases (70.7%). In one case demonstrated I.P. persistent (1.7%) and never one case demonstrated relapsed.
Conclusions. The authors think that the scintigraphy toghether with the echography show high sensibility to identification the pathological glands. Neck surgical exploration can still give the side good when the diameter of the parathyroids is inferior to 5 mm.