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Panminerva Medica 2000 Giugno;42(2):141-9

lingua: Inglese

Tourette’s syndrome in children: neurological, neuropsychological and psychiatric issues

Brovedani P., Masi G.

From the Division of Child Neurology and Psychiatry University of the Study, Pisa IRCCS Stella Maris, Calambrone, Pisa


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The inter­play ­between neu­ro­log­ic, neu­ro­psy­cho­log­ic and psy­chi­at­ric fea­tures ­makes Tourette’s syndrome (TS) a par­a­dig­mat­ic mod­el for neu­ro­psy­chi­at­ric dis­or­ders. The aim of ­this ­paper is to ­review ­this com­plex inter­play of clin­i­cal fea­tures. After a sur­vey of ­some epi­dem­i­olog­i­cal stud­ies, the nat­u­ral his­to­ry of neu­ro­log­i­cal, behav­ior­al and psy­cho­log­i­cal char­ac­ter­is­tics of the syn­drome is ­described. The prob­lem of ­high psy­chi­at­ric comor­bid­ity, first­ly ­with obses­sive-com­pul­sive dis­or­der and atten­tion def­i­cit-hyper­ac­tiv­ity dis­or­der, is dis­cussed. Neuropsycholo-gical fea­tures of TS are con­sid­ered, as ­they can neg­a­tive­ly ­affect the qual­ity of ­life of affect­ed ­patients. Consi-derations on treat­ment, phar­mac­o­log­ic as ­well as edu­ca­tion­al and psy­cho­ther­a­peu­tic, con­clude ­this ­review.

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