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Panminerva Medica 1999 Dicembre;41(4):367-9

lingua: Inglese

Tubercolosis and Pelger-Huët anomaly. Case ­report

Cicchitto G., Parravicini M., De Lorenzo S., Di Pisa G., Malacrida A.

From the Division of Pneumophtisiology * Clinical Laboratory “E. Morelli” Hospital, Sondalo (SO), Italy


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We ­describe a ­patient ­with pul­mo­nary tuber­cu­losis and a ­rare dis­tur­bance of leu­ko­cyte seg­men­ta­tion, ­known as “Pelger-Huët ­anomaly”, ­which can be ­observed in var­ious dis­eases ­such as malig­nan­cies and/or infec­tions. The impor­tance of ­this asso­ci­a­tion is equiv­ocal: ­some ­authors ­have ­related to the asso­ci­a­tion the par­tic­ular ­severity of tuber­cu­losis or the ­death ­they ­observed; in the ­case ­reported we ­noted no evi­dence of ­such a rela­tion, not­with­standing the pres­ence of the homo­zy­gous ­form of the Pelger-Huët ­anomaly. We sug­gest there­fore ­that, ­when Pelger-Huët ­anomaly is ­found, an under­lying dis­ease ­should be ­searched for; the ­course of ­this ill­ness, how­ever, ­might not be ­affected.

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