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THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Rivista di Medicina Nucleare e Imaging Molecolare


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
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REVIEWS  HEAD AND NECK TUMORS


The Quarterly Journal of Nuclear Medicine and Molecular imaging 2011 Ottobre;55(5):500-8

lingua: Inglese

FDG-PET/CT for detection of the unknown primary head and neck tumor

Johansen J. 1, Petersen H. 2, Godballe C. 3, Loft A. 4, Grau C. 5

1 Department of Oncology, Odense University Hospital, Odense Denmark
2 PET-Center, Odense University Hospital, Odense Denmark
3 Department of ENT Head and Neck Surgery, Odense University Hospital, Odense Denmark
4 PET and Cyclotron Unit, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
5 Department of Oncology, Aarhus University Hospital, Aarhus, Denmark


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The benefit of FDG-PET in addition to standard work-up for carcinoma of unknown primary (CUP) and metastatic neck lesions has been widely described. However, most studies have been of retrospective nature with large heterogeneities in terms of workup standards and patient selection leaving several questions to be answered regarding the real value of PET in CUP. We here present an overview of the literature with focus on the current evidence of FDG-PET in detecting a primary in CUP and discuss the rationale of PET/CT in the diagnostic armamentarium of CUP.

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j.johansen@dadlnet.dk