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ULTIMO FASCICOLOTHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Rivista di Medicina Nucleare e Imaging Molecolare


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
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The Quarterly Journal of Nuclear Medicine and Molecular imaging 2011 Ottobre;55(5):487-99

HEAD AND NECK TUMORS 

 REVIEWS

Role of FDG-PET/CT in staging and follow-up of head and neck squamous cell carcinoma

D. Mak 1., Corry J. 1, Lau E. 2, 3, Rischin D. 4, 5, Hicks R. J. 2, 3, 5

1 Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Australia;
2 Centre for Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Australia;
3 Department of Radiology, University of Melbourne, Parkville, VIC, Australia;
4 Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia;
5 Department of Medicine, University of Melbourne, Parkville, VIC, Australia

The established and emerging roles of FDG positron-emission tomography/computed tomography (PET/CT) in the evaluation of squamous cell carcinoma of head and neck region is reviewed with a strong clinical focus on recommended applications and methodologies. In the staging of newly diagnosed disease, detection of cervical nodal involvement is the major indication but exclusion of distant metastases and of synchronous primary malignancy is also a valuable adjunct. Use in radiotherapy planning is advantageous for locally-advanced disease. Although there are few data yet to assess the use of FDG PET/CT to assess response during therapy, there is good evidence that this technique can accurately assess the post-treatment neck to identify those who might benefit from salvage therapy and those in whom observation or palliative treatment might be more appropriate. Although more expensive than other imaging modalities used for assessing this disease, the superior diagnostic accuracy and impact of incremental information provided by this technology has been shown to be cost-effective in several clinical scenarios.

lingua: Inglese


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