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THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Rivista di Medicina Nucleare e Imaging Molecolare


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
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REVIEWS  SPECIAL ISSUE ON PET/CT AND RADIOTHERAPY


The Quarterly Journal of Nuclear Medicine and Molecular imaging 2010 October;54(5):500-9

lingua: Inglese

Hypoxia PET/CT imaging: implications for radiation oncology

Arabi M., Piert M.

Department of Radiology, Division of Nuclear Medicine, University of Michigan Health System, Ann Arbor, MI, USA


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Hypoxia, a condition of reduced partial pressure of oxygen in tissue, is an important determinant of poor tumor response to radiation treatment. Many invasive and non-invasive methods and approaches have been investigated to detect tumor hypoxia for response prediction and to facilitate modulation of radiation treatment. In this review we discuss the biological consequences of tumor hypoxia, methods of measuring regional tumor hypoxia with positron emission tomography (PET) tracers and applications for radiation oncology.

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mpiert@umich.edu