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ULTIMO FASCICOLOTHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Rivista di Medicina Nucleare e Imaging Molecolare


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
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The Quarterly Journal of Nuclear Medicine 1999 Dicembre;43(4):297-306

ENDOCRINOLOGY - II
Therapy 

The ­role of nucle­ar med­i­cine in the man­age­ment of Graves’ dis­ease

Freitas J. E.

From the Nuclear Medicine Services St. Joseph Mercy Hospital, Ann Arbor, MI, USA Internal Medicine University of Michigan Medical School, Ann Arbor, MI, USA

131I ther­a­py is ­safe and effec­tive for ­most Graves’ dis­ease ­patients. It is ­being ­used ­more fre­quent­ly in pre­vi­ous­ly restrict­ed pop­u­la­tions ­such as chil­dren, ado­les­cents, and wom­en of child­bear­ing age. It ­affords ­prompt, con­sis­tent ­relief of hyper­thyr­oi­dism, but per­ma­nent hypo­thy­roid­ism ­ensues in ­almost all ­patients. This com­pli­ca­tion is read­i­ly diag­nosed ­with mod­ern in ­vitro ­assays and inex­pen­sive, ­life-­long replace­ment ther­a­py ren­ders the ­patient asymp­to­mat­ic and ­able to ­resume a nor­mal life­style. Recent chang­es in NRC require­ments ­have fur­ther lib­er­al­ized the use of 131I for Graves’ dis­ease in the USA, per­mit­ting ­more ­patients to be treat­ed ­with effec­tive out­pa­tient ther­a­py. The con­tro­ver­sial ­role of 131I in exac­er­ba­tion of GO has ­been fur­ther clar­i­fied and pre­ven­tive meas­ures are avail­able.

lingua: Inglese


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